Nasfat Shehadeh, MD

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Dr. Nasfat Shehadeh is board certified in Hematology, Medical Oncology. His clinical interests include GU/ GI oncology and head/neck cancer. Dr. Shehadeh has been voted a top doctor in medical oncology for years 2019-2022 by Charlotte Magazine.

He graduated from the medical school at Jordan University of Science and Technology in Irbid, Jordan with honors on the Dean’s list. After his residency and fellowship at Wayne State University in Detroit, he held various academic appointments as a fellow and professor at the University of Minnesota, Karmanos Cancer Institute in Detroit, and University of Toledo.

Before serving cancer patients in Charlotte, he was the medical director at Mercy Cancer Centers in Toledo and an Assistant Professor of Medicine at the University of Minnesota in Minneapolis. He and his family migrated south when he took on the clinical role of developing a cancer program with Novant Health Cancer Specialists starting in 2015. In 2020, Dr. Shehadeh joined the oncology team at OSC. Having worked previously in a hospital-based cancer program, he has seen the vast difference of personalized care that can be obtained in an independent oncology practice. The setting is patient-focused with access to care that is broadened across all the hospital systems and not being limited to just one.

Dr. Shehadeh brings a range of clinical expertise in all areas of solid tumor and blood diseases. He has overseen many clinical research trials in various cancer therapies, including immunotherapy, metastasized cellular structure, stem cell transplant, and blood disorders, to name a few. In the past few years he has been presenting to various cancer groups on specific topics in lung cancer, breast cancer, clinical trials, colon cancer, and multiple myeloma. He is a member of the American Society of Clinical Oncology, Community Oncology Alliance, and locally the Independent Physicians of the Carolinas.

Dr. Shehadeh is married with four children. In his leisure time, he enjoys singing and music. You can also find him spending time camping with his kids, hiking, playing ping-pong, and chess. Dr. Shehadeh is a dedicated volunteer at the Shifa Clinic, which provides free health care for those in need.


Education & Training

ResidencyWayne State University Detroit Medical Center
Medical SchoolJordan University of Science and Technology
FellowshipsHematology/Oncology Karmanos Cancer Institute Wayne State University Detroit Medical Center
InternshipsZarka Teaching Hospital
Board CertificationsMedical Oncology, Hematology, Internal Medicine

Patient Reviews

  • "Excellent Staff and PA, Genaro, along with the knowledgeable and courteous Dr Shahedeh. Professional. It was a pleasure to visit. Top notch experience. Highly recommended."
      5.0 Stars - (2026-09-11)
  • "very thorough, stand upfront with you"
      5.0 Stars - (2026-09-03)
  • "Vincent Johnson experienced Dr. Shehadeh and his staff on 9.2.2026. What a highly qualified and knowledgeable physician. The entire experience with him and his PA was remarkable. I feel very confident in my care with Dr. Shehadeh."
      5.0 Stars - (2026-09-03)
  • "Excellent staff throughout the entire operation."
      5.0 Stars - (2026-09-03)
  • "Great team. Everyone is so professional."
      5.0 Stars - (2026-08-29)
  • "He is the best Dr. I had the chance to be treated with him. He is knowledgeable of what he does. When he prescribe medication to you he makes sure you understand the meditation very well."
      5.0 Stars - (2026-08-28)
  • "Friendly helpful staff. Dr. Shehadeh is very caring, thorough and easy to talk to. I would recommend this office without hesitation."
      5.0 Stars - (2026-08-26)
  • "I am very pleased with the treatment I receive from all the staff at Carolina Oncology Specialist. Dr. Shehadeh is outstanding. He has been sensitive and supportive throughout my journey. I’m very happy with the organization."
      5.0 Stars - (2026-08-13)
  • "If you’re going to have to deal with cancer in any of it’s ugly forms, do yourself a favor and seek out Dr Nasfat Shehadeh for treatment. He is extremely knowledgable, compassionate and has a sense of humor (pretty important when you’re dealing with this thing). Every time I leave his office or finish a treatment, I just feel like everything’s going to be ok."
      5.0 Stars - (2026-08-12)
  • "Beautiful place Beautiful people"
      5.0 Stars - (2026-08-12)