Dr. O’Keefe specializes in general oncology, staying up-to-date with all different disease states and new treatment developments. She has a special interest in caring for breast and gynecological cancer patients, as well as patients with gastrointestinal cancers such as colon, pancreatic, and liver cancers. Dr. O’Keefe also expresses a keen interest in enrolling patients in clinical trials to advance the science, particularly when these trials offer improved treatment options. Moreover, she is dedicated to enhancing the care, comfort, and overall quality of life for every patient throughout their journey, ensuring dignity, grace, and peace at all stages of care.
Dr. O’Keefe treats the whole person, taking a patient-centered approach to care that is based on listening intently and understanding what patients want to achieve from treatment. Dr. O’Keefe said, “I am acutely aware of the impact that a patient’s cancer diagnosis and treatment journey can have on them as
individuals and for their family. I am passionate about making a difference in my patients’ lives. My patients and their family members are the most important people in the room. I am responsible for educating them with relevant information about their disease, alleviating their concerns at each stage in the process, and developing a high-quality, cost-effective treatment plan that best fits their individual needs. I am committed to making each patient feel empowered by the information provided to them and supported by the expertise of their care team.”
Dr. O’Keefe’s received her Doctor of Osteopathic Medicine degree from Edward Via College of Osteopathic Medicine. She then completed her Internal Medicine Residency at Carolinas Medical Center and Hematology/Oncology Fellowship at Atrium Health Levine Cancer Institute. During her fellowship, Dr. O’Keefe was named Chief Fellow.
Outside the office, Dr. O’Keefe enjoys spending time with her husband Ryan and extended family including her nieces and nephews, traveling internationally to new places and cultures, and staying active by running, hiking with their dog, and swimming. She is on a quest to become a better cook, become fluent in Spanish, and continue to be active in global medical mission trips in the future.
Patient Reviews
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"Dr O’Keefe is not only knowledgeable, understanding and compassionate- She takes the time to listen to the whole picture. She investigates and wants the best She for sure meets you where you are. She is the first doctor since we moved to Charlotte 3 years ago that is their word with follow through and care. All doctors should learn from Dr O’Keefe"
5.0 Stars - (2026-10-26) -
"Dr. O'Keefe was great. professional and engaging. I got the best support is could have expected. Beginning on my journey to deal with Mycosis Fungoids and hope she can be with me."
5.0 Stars - (2026-10-25) -
"I am pleased with my two recent visits. The staff was friendly and prompt with seeing me . I appreciate their providing me with a paper copy of my lab results."
5.0 Stars - (2026-10-20) -
"The Staff and Dr. O'Keefe were amazing, comforting,and knowledgeable.Guiding a patient through the possibility of having cancer is not easy and they make you feel that you are not alone!"
5.0 Stars - (2026-10-18) -
"Dr O’Keefe is fantastic."
5.0 Stars - (2026-09-30) -
"This is the most amazing down to earth Doctor, she's actually a family member now cause my mom has fell in love with her. The treatments suggested seems to help every time something needs to be adjusted, (when we follow) I trust her with my mom's life!!!!"
5.0 Stars - (2026-09-25) -
"Responsive and helpful"
5.0 Stars - (2026-09-18) -
"Finding out you have cancer is one of the scariest things I’ve ever been through, My husband searched for good doctors and when we saw Kaitlyn OKeefe we knew she’d be the one. I just had a really good feeling and I have to say I was right. she has so much compassion and she’s so nice and kind and she’s there whenever I need her advice on something. I’m so happy that I found her because this is so hard. She actually listens and takes the time. Thank you Lord for sending it to me.❤️"
5.0 Stars - (2026-09-16) -
"Kaitlyn and her NP are the absolute best! So professional but so kind and loving. Would highly recommend them."
5.0 Stars - (2026-09-12) -
"Dr. O'Keefe was very professional, I have a second visit already scheduled with her."
5.0 Stars - (2026-09-02)